It's extremely poisonous and carcinogenic (meaning it can cause cancer). The solvent anhydrous hydrazine, for example, may explode when heated. If working with toxic ergot weren't hazardous enough, the solvents and reagents (compounds used to bring about chemical reactions) are also incredibly dangerous. In fact, LSD itself may break down quickly when exposed to light. The darkroom setup becomes necessary here, because the fungus will decompose under bright lights. Remember the people poisoned by rye bread in the Middle Ages? Once the chemist obtains the fungus, he has to carefully and precisely culture it to extract the ergot alkaloids (an alkaloid is a compound containing basic nitrogen atoms). LSD chemists must be extremely careful in working with ergot because of its toxicity. Here, we'll look at a recipe that starts with ergot, the substance that made Albert Hofmann famous in the first place. It's considered a precursor to LSD, although the amount of LSA in different seeds varies so much that the quality of the drug made from it would also vary. The LSA can be extracted from the seeds and produce a mild high on its own. Morning glory seeds and the seeds of some related plants contain LSA, or lysergic acid amide. Other online recipes call for morning glory seeds, which can be especially dangerous because they're often sold with a toxic coating to discourage consumption. Some "recipes" may start with lysergic acid. There a couple of different ways to make LSD.